At first it seemed like it helped now I feel the same as before I started taking the medicine other than the fact that none of my clothes fit and there is a lot more of me to carry around. Anyone know if I quit taking it if the weight will fall back off I started Hydroxychloroquine 2 weeks ago. One week in and I thought this may just work, except for the ‘extra itchiness’ I seemed to get every night. H-chloroquine 200mg Plaquenil and alcohol Hydroxychloroquine is a DMARD. The brand name is Plaquenil. What does Plaquenil do? Plaquenil relieves pain and swelling and prevents damage to joints. How long does Plaquenil take to work? Plaquenil works very slowly. In 1 to 3 months you should start to feel better. You may continue to get better for up to 1 year. Symptoms while waiting for hydroxychloroquine to work. How is hydroxychloroquine taken? Hydroxychloroquine is taken by mouth in tablet form. The usual dose is one tablet 200mg once or twice a day. Tablets can be taken altogether, once a day. The dose may be reduced to a maintenance dose after a few months once a response is achieved. Originally, hydroxychloroquine was used to prevent and treat malaria and was considered very effective. Now it is generally used for rheumatoid arthritis, but it has also been shown to work well for juvenile arthritis, some lupus symptoms, and other types of autoimmune conditions. I was prescribed this drug to ease my ra disease, I was taking 400mg per day which was to last for 3 months then reduced to 200mg. Right before I hit the two week mark, I woke up with my heart racing and continued feeling my heart flutter all day and I just felt week and tired. After msging Rheum, decided to stop taking meds to see how I feel and continue with the AIP to handle symptoms and try to work at ‘healing from inside out! Time will tell and I’m eager to see how much the AIP is helping once odd meds. Months for hydroxychloroquine to work on joints Common Questions About Taking Methotrexate for Rheumatoid., PATIENT NFORMATION ON HYDROXYCHLOROQUINE Hydroxychloroquine tablet costPlaquenil maculopathy reportHydroxychloroquine pka About 60% of people treated with hydroxychloroquine experience improvement in their condition. Hydroxychloroquine does not work straight away. It may take 8 to 12 weeks for symptoms to start to improve. The full effect of treatment may take up to 26 weeks. ATIENT NFORMATION ON HYDROXYCHLOROQUINE. RA and Hydroxychloroquine How Effective is it for Rheumatoid Arthritis.. How long did hydroxychloroquine take to work. - HealthUnlocked. If you are taking hydroxychloroquine over a long duration, it is important to take eye exams every 6 to 12 months. 6 Do not take hydroxychloroquine if you experience vision symptoms, including problems seeing or reading, light sensitivity, blurred distance vision, or light flashes or streaks. Indicates that you can expect to see some results after a month or two of taking hydroxychloroquine, but in order to get the full benefits you will need to take the medication for at least six months. That can help you realize how much benefit you’re going to actually get from the drug. Symptoms can start to improve in one to two months, but it may take up to six months before the full benefits of this medication are experienced. Side Effects Hydroxychloroquine typically is very well tolerated.