The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. A secondary aim is to determine whether certain patient features will predict response to sertraline, naltrexone or the combination of the two drugs. Listing a study does not mean it has been evaluated by the U. Subjects will be randomized into treatment groups for 14 weeks. This study will examine depressed alcoholic outpatients to assess whether combining naltrexone (Revia) and sertraline (Zoloft) will result in greater reductions in both drinking and depression over either medication alone or placebo. The followup phase includes two visits at 6 and 9 months after treatment. The proposed study will examine managing relapse in patients with alcohol dependence and depression using a 14-week double-blind, placebo-controlled, combination of 100 mg/day of naltrexone, 200 mg/day of sertraline, and individual, cognitive behavioral therapy (CBT). For testing the medication, the design will be 2x2, consisting of four groups: naltrexone/sertraline, naltrexone only, sertraline only, placebo. All four groups will receive once weekly sessions of CBT given by therapists experienced in working with patients with substance disorders and trained in the principles of CBT. Don't stop taking an antidepressant or other medication just so that you can drink. Most antidepressants require taking a consistent, daily dose to maintain a constant level in your system and work as intended. Stopping and starting your medications can make your depression worse. While it's generally best not to drink at all if you're depressed, ask your doctor. If you have depression: If you're concerned about your alcohol use, you may benefit from substance abuse counseling and treatment programs that can help you overcome your misuse of alcohol. Joining a support group or a 12-step program such as Alcoholics Anonymous may help. If you're at low risk of addiction to alcohol, it may be OK to have an occasional drink, depending on your particular situation, but talk with your doctor. Fluconazole 100mg tablets Wellbutrin 50 Buy proscar cheap Viagra is used for what purpose Alcohol can also cause sedation and may enhance these effects from Zoloft. That means if you mix alcohol and Zoloft, you may experience the drowsy effects more quickly than someone who drinks the. However, alcohol also affects your serotonin levels. Zoloft can also lower your heart rate and blood pressure. Some patients report that taking Zoloft can actually cause them to crave more alcohol. This could be extremely dangerous when you combine the effects of both of these substances. Consuming alcohol and Zoloft can be risky combo. Side Effects of Taking Zoloft with Alcohol. Amplifies Depression; After drinking alcohol, you may experience a mood elevation for a short period. However, it also has a tendency to reduce the effectiveness of Zoloft, thereby making the symptoms of depression even worse. Sertraline is a type of antidepressant known as a selective serotonin reuptake inhibitor (SSRI). It's often used to treat depression, and also sometimes panic attacks, obsessive compulsive disorder (OCD) and post-traumatic stress disorder (PTSD). Sertraline helps many people recover from depression, and has fewer unwanted side effects than older antidepressants. Sertraline comes as tablets, which are available only on prescription. Sertraline can be taken by adults for depression or obsessive compulsive disorder. Sertraline can be taken by children aged 6 to 17, but only for obsessive compulsive disorder. Check with your doctor before starting to take sertraline if you: If you have diabetes, sertraline can make it more difficult to keep your blood sugar stable. You can choose to take sertraline at any time, as long as you stick to the same time every day. You should avoid or limit the use of alcohol while being treated with sertraline. Alcohol can increase the nervous system side effects of sertraline such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. Talk to your doctor or pharmacist if you have any questions or concerns. Sertraline alcohol A Double-blind, Randomized Trial of Sertraline for Alcohol., Alcohol And Zoloft - A Dangerous Combination? - Alcoholism. Propecia what to expectPrednisone for pneumoniaMetformin 800 mg Read all of this leaflet carefully before you start taking this medicine because it contains important information for you. - Keep this may need to read Sertraline 50 mg film-coated tablets Sertraline 100 mg.. Zoloft and Alcohol - 9 Serious Side Effects to Know. Sertraline an antidepressant - NHS. Zoloft and alcohol act upon similar chemicals in the brain, which means that Zoloft could intensify the effects of the alcohol. If a person chooses to drink alcohol while taking this medication, he or she should only consume light to moderate amounts of alcohol. Alcohol avoid alcohol while you are taking sertraline, especially when you first start treatment. Drinking alcohol while taking SSRIs can cause. With alcohol and Zoloft or alcohol and any antidepressant, there’s another reason the two don’t mix. Since alcohol is a depressant and it impacts your brain, it can make the underlying symptoms Zoloft is treating worse.