Valacyclovir zoster

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  1. Medvezhonok Moderator

    Valacyclovir zoster


    Artikel ini memberikan informasi dasar tentang topik kesehatan. Informasi dalam artikel ini boleh digunakan hanya untuk penjelasan ilmiah, bukan untuk diagnosis diri dan tidak dapat menggantikan diagnosis medis. Perhatian: Informasi dalam artikel ini bukanlah resep atau nasihat medis. Herpes zoster ditularkan antarmanusia melalui kontak langsung, salah satunya adalah transmisi melalui pernapasan sehingga virus tersebut dapat menjadi epidemik di antara inang yang rentan. Risiko terjangkit herpes zoster terkait dengan pertambahan usia. Hal ini berkaitan adanya immunosenescence, yaitu penurunan sistem imun secara bertahap sebagai bagian dari proses penuaan. Selain itu, hal ini juga terkait dengan penurunan jumlah sel yang terkait dalam imunitas melawan virus varicella-zoster pada usia tertentu. Penderita imunosupresi, seperti pasien HIV/AIDS yang mengalami penurunan CD4 sel-T, akan berpeluang lebih besar menderita herpes zoster sebagai bagian dari infeksi oportunistik. Shingles is a viral disease produced by the varicella zoster virus (VZV), the same virus that causes chicken pox. Its symptoms include pain and a blistering rash that occurs along the nerves that contain dormant virus. However, you can catch chicken pox through direct contact with someone who has shingles, by touching the area of the rash. It sometimes infects younger people, or people with a weakened immune system. The disease starts with tingling, itchiness, or pain on an infected person's skin. After a few days, the disease causes a blistering rash. The rash grows into small blisters filled with fluid. These blisters dry out and crust over for several days. The rash causes anything from mild itching to extreme pain. The shingles virus is contagious from person to person only by direct contact. For this reason, persons with shingles are advised to limit contact with those who are not immune to chicken pox, those with increased risk are young children and pregnant women. Contracting chickenpox when one is pregnant can be dangerous to the unborn child.

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    Valaciclovir, also spelled valacyclovir, is an antiviral drug used in the management of herpes simplex, herpes zoster shingles, and herpes B. It is a prodrug, which. Medication is generally recommended as the standard first-line treatment for herpes zoster ophthalmicus infections. Both acyclovir and its prodrug valacyclovir. Both valacyclovir and famciclovir effectively decrease the duration of acute pain in herpes zoster and in post-herpetic neuralgia, usually defined.

    2 g orally every 12 hours for a total of 2 doses HIV-infected adult (guideline dosing): 1 g orally twice a day for 5 to 10 days Comments: -Therapy should be started at the earliest sign of a cold sore, e.g. -Efficacy of treatment when initiated after the development of clinical signs of a cold sore have not been established. -Guidelines for the Prevention and Treatment of Opportunistic Infections Among HIV- Infected Adults and Adolescents may be consulted for additional guidance. Use: For the treatment of cold sores (herpes labialis). Genital Herpes: FIRST EPISODE: 1 g orally twice a day Duration of therapy: 10 days (manufacturer): 7 to 10 days (CDC recommendation) RECURRENT EPISODES: 500 mg orally twice a day for 3 days OR 1 g orally once a day for 5 days -Therapy should be started at the first sign of a genital herpes episode Comments: -All patients with newly acquired genital herpes should receive antiviral therapy as first episodes can cause a prolonged clinical illness, even among persons with mild clinical manifestations initially. -Therapy for the initial episode is most effective when administered within 48 hours of onset of signs and symptoms; the efficacy or initiating treatment more than 72 hours after onset of signs and symptoms has not been established. -For recurrent episodes, the efficacy of starting more than 24 hours after onset of signs and symptoms has not been established. -CDC STD treatment Guidelines may be consulted for additional guidance. Valaciclovir, also spelled valacyclovir, is an antiviral drug used in the management of herpes simplex, herpes zoster (shingles), and herpes B. It is a prodrug, which is converted to aciclovir in a persons body. Common adverse drug reactions (≥1% of patients) associated with valaciclovir therapy are the same as for aciclovir, its active metabolite, and include: nausea, vomiting, diarrhea and headache. Infrequent adverse effects (0.1–1% of patients) include: agitation, vertigo, confusion, dizziness, edema, arthralgia, sore throat, constipation, abdominal pain, rash, weakness and/or renal impairment. Rare adverse effects ( Valaciclovir belongs to a family of molecules first described and patented by Paolo Cornaglia Ferraris in 1982 (patents EP0077460 A2, CA1258149A1, DE3273785D1, EP0077460A3, EP0077460B1, US4567182). Valaciclovir is a prodrug, an esterified version of aciclovir that has greater oral bioavailability (about 55%) than aciclovir (10–20%). It is converted by esterases to the active drug aciclovir, as well as the amino acid valine, via hepatic first-pass metabolism.

    Valacyclovir zoster

    Valacyclovir Dosage Guide with Precautions -, Valacyclovir versus acyclovir for the treatment of herpes zoster.

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  7. Acyclovir treatment of acute herpes zoster speeds rash healing and decreases. zoster. Valaciclovir Valtrex, the l-valyl ester of acyclovir, is rapidly converted to.

    • Valaciclovir compared with acyclovir for improved therapy for herpes..
    • Valacyclovir or Famciclovir for Herpes Zoster? - NEJM Journal Watch.
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    Patients received valacyclovir prophylaxis orally at a dose of 500 mg daily. Varicella zoster virus VZV reactivation herpes zoster is one adverse event of. For the treatment of herpes zoster shingles infection. NOTE Valacyclovir is not approved for the treatment of disseminated herpes zoster infections. Skin-nontumor - Herpes simplex or varicella zoster. Cite this page Hamodat, M. Herpes simplex or varicella zoster. website.

     
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