Prednisolone acetate ophthalmic suspension (eye drops) is an adrenocortical steroid product, prepared as a sterile ophthalmic suspension and used to reduce swelling, redness, itching, and allergic reactions affecting the eye. Although there are no major human studies of prednisolone use in pregnant women, studies in several animals show that it may cause birth defects including increase cleft palate. Prednisolone should be used in pregnant women when benefits outweigh the risks and children born from mothers using prednisolone during pregnancy should be monitored for impaired adrenal function. Prednisolone is found in breast milk of mothers taking prednisolone. As a glucocorticoid, the lipophilic structure of prednisolone allows for easy passage through the cell membrane where it then binds to its respective glucocorticoid receptor (GCR) located in the cytoplasm. Upon binding, formation of the GC/GCR complex causes dissociation of chaperone proteins from the glucocorticoid receptor enabling the GC/GCR complex to translocate inside the nucleus. Once inside the nucleus, the homodimer GC/GCR complex binds to specific DNA binding-sites known as glucocorticoid response elements (GREs) resulting in gene expression or inhibition. Complex binding to positive GREs leads to synthesis of anti-inflammatory proteins while binding to negative GREs block the transcription of inflammatory genes. Being a customer centric organization, we are involved in manufacturing, exporting and supplying a supreme quality range of Prednisolone-21-Acetate in Guangzhou, Guangdong, China. Name: Prednisolone-21-acetate Synonym:(11beta)-21-(Acetyloxy)-11, 17-dihydroxypregna-1, 4-diene-3, 20-dione;11, 17-Dihydroxy-3, 20-dioxopregna-1, 4-dien-21-yl acetate;11beta, 17, 21-Trihydroxypregna-1, 4-diene-3, 20-dione 21-acetate;21-(acetyloxy)-11, 17-dihydroxy-4-diene-(11-beta)-pregna-20-dione;21-(acetyloxy)-11, 17-dihydroxy-4-diene-(11beta)-pregna-20-dione;4-diene-3, 20-dione, 11-beta, 17, 21-trihydroxy-pregna-21-acetate; Ak-Tate;component of Blephamide liquifilm, CAS：52-21-1M. W:402.48Appearance: White powderstorage:2-8°Cshelf life:18 months Application: Pharmaceutical raw materials Established in 2002, GUANGZHOU KAFEN BIOTECH CO., LTD. has been a leading name in offering top notch Pharmaceutical Chemicals. Located in Guangzhou, Guangdong, we offer the best quality Prednisolone-21-Acetate to our customers at best prices in the industry. Zoloft with trazodone Prednisone blood sugar Doxycycline and cheese Prednisolone is a steroid medication used to treat certain types of allergies, inflammatory. Prednisolone acetate ophthalmic suspension eye drops is an. or 1,2-dehydrohydrocortisone, as well as 11β,17α,21-trihydroxypregna-1,4-diene-3. ChemicalBook ProvidePrednisolone-21-acetate 52-21-1IR2IR2,MS,IR3,IR1,1HNMR,Raman,ESR,13CNMR,Spectrum. Structure, properties, spectra, suppliers and links for Prednisolone acetate, 52-21-1. Prednisone is used for many different autoimmune diseases and inflammatory conditions, including asthma, COPD, CIDP, rheumatic disorders, allergic disorders, ulcerative colitis and Crohn's disease, adrenocortical insufficiency, hypercalcemia due to cancer, thyroiditis, laryngitis, severe tuberculosis, hives, lipid pneumonitis, pericarditis, multiple sclerosis, nephrotic syndrome, sarcoidosis, to relieve the effects of shingles, lupus, myasthenia gravis, poison oak exposure, Ménière's disease, autoimmune hepatitis, giant-cell arteritis, the Herxheimer reaction that is common during the treatment of syphilis, Duchenne muscular dystrophy, uveitis, and as part of a drug regimen to prevent rejection after organ transplant. It is important in the treatment of acute lymphoblastic leukemia, non-Hodgkin lymphomas, Hodgkin's lymphoma, multiple myeloma, and other hormone-sensitive tumors, in combination with other anticancer drugs. Prednisone can be used in the treatment of decompensated heart failure to increase renal responsiveness to diuretics, especially in heart failure patients with refractory diuretic resistance with large dose of loop diuretics. In terms of the mechanism of action for this purpose: prednisone, a glucocorticoid, can improve renal responsiveness to atrial natriuretic peptide by increasing the density of natriuretic peptide receptor type A in the renal inner medullary collecting duct, inducing a potent diuresis. Short-term side effects, as with all glucocorticoids, include high blood glucose levels (especially in patients with diabetes mellitus or on other medications that increase blood glucose, such as tacrolimus) and mineralocorticoid effects such as fluid retention. The mineralocorticoid effects of prednisone are minor, which is why it is not used in the management of adrenal insufficiency, unless a more potent mineralocorticoid is administered concomitantly. 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Then, about three months ago I tried MAXIDUS, and was blown away. Prednisolone 21-acetate Prednisone acetate C23H28O6 - PubChem, Prednisolone-21-acetate 52-21-1IR2 - ChemicalBook Safe site to purchase cialisTadalafil versus sildenafilWhere to purchase accutane Offers 186 prednisolone-21-acetate products. such as free samples, paid samples. Prednisolone-21-acetate, Prednisolone-21-acetate. -.. Prednisolone acetate C23H30O6 ChemSpider. Gentamicin and prednisolone acetate ophthalmic suspension.. Pred Forte ® prednisolone acetate ophthalmic suspension, USP 1% is a sterile, topical anti-inflammatory agent for ophthalmic use. Its chemical name is 11ß,17, 21-Trihydroxypregna-1,4-diene-3, 20-dione 21-acetate and it has the following structure PubChem CID 5834. Chemical Names Prednisolone acetate; 52-21-1; Omnipred; Pricortin; Prediacortine; Cormalone More. Molecular Formula C23H30O6. Sigma-Aldrich offers a number of Prednisolone acetate products. View information & documentation regarding Prednisolone acetate, including CAS, MSDS & more.