Prednisolone 21-acetate

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  1. Dima69 Well-Known Member

    Prednisolone 21-acetate


    Prednisolone acetate ophthalmic suspension (eye drops) is an adrenocortical steroid product, prepared as a sterile ophthalmic suspension and used to reduce swelling, redness, itching, and allergic reactions affecting the eye. Although there are no major human studies of prednisolone use in pregnant women, studies in several animals show that it may cause birth defects including increase cleft palate. Prednisolone should be used in pregnant women when benefits outweigh the risks and children born from mothers using prednisolone during pregnancy should be monitored for impaired adrenal function. Prednisolone is found in breast milk of mothers taking prednisolone. As a glucocorticoid, the lipophilic structure of prednisolone allows for easy passage through the cell membrane where it then binds to its respective glucocorticoid receptor (GCR) located in the cytoplasm. Upon binding, formation of the GC/GCR complex causes dissociation of chaperone proteins from the glucocorticoid receptor enabling the GC/GCR complex to translocate inside the nucleus. Once inside the nucleus, the homodimer GC/GCR complex binds to specific DNA binding-sites known as glucocorticoid response elements (GREs) resulting in gene expression or inhibition. Complex binding to positive GREs leads to synthesis of anti-inflammatory proteins while binding to negative GREs block the transcription of inflammatory genes. Being a customer centric organization, we are involved in manufacturing, exporting and supplying a supreme quality range of Prednisolone-21-Acetate in Guangzhou, Guangdong, China. Name: Prednisolone-21-acetate Synonym:(11beta)-21-(Acetyloxy)-11, 17-dihydroxypregna-1, 4-diene-3, 20-dione;11, 17-Dihydroxy-3, 20-dioxopregna-1, 4-dien-21-yl acetate;11beta, 17, 21-Trihydroxypregna-1, 4-diene-3, 20-dione 21-acetate;21-(acetyloxy)-11, 17-dihydroxy-4-diene-(11-beta)-pregna-20-dione;21-(acetyloxy)-11, 17-dihydroxy-4-diene-(11beta)-pregna-20-dione;4-diene-3, 20-dione, 11-beta, 17, 21-trihydroxy-pregna-21-acetate; Ak-Tate;component of Blephamide liquifilm, CAS:52-21-1M. W:402.48Appearance: White powderstorage:2-8°Cshelf life:18 months Application: Pharmaceutical raw materials Established in 2002, GUANGZHOU KAFEN BIOTECH CO., LTD. has been a leading name in offering top notch Pharmaceutical Chemicals. Located in Guangzhou, Guangdong, we offer the best quality Prednisolone-21-Acetate to our customers at best prices in the industry.

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    Prednisone is a glucocorticoid medication mostly used to suppress the immune system and decrease inflammation in conditions such as asthma, COPD, and rheumatologic diseases. It is also used to treat high blood calcium due to cancer and along with other steroids for adrenal insufficiency. It BPR regulation aims to improve the functioning of the biocidal products market in the EU, while ensuring a high level of protection for humans and the environment. Offers 73 prednisolone 21 acetate powder products. About 24% of these are auxiliaries and other medicinal chemicals, 12% are pharmaceutical intermediates.

    Prednisone is used for many different autoimmune diseases and inflammatory conditions, including asthma, COPD, CIDP, rheumatic disorders, allergic disorders, ulcerative colitis and Crohn's disease, adrenocortical insufficiency, hypercalcemia due to cancer, thyroiditis, laryngitis, severe tuberculosis, hives, lipid pneumonitis, pericarditis, multiple sclerosis, nephrotic syndrome, sarcoidosis, to relieve the effects of shingles, lupus, myasthenia gravis, poison oak exposure, Ménière's disease, autoimmune hepatitis, giant-cell arteritis, the Herxheimer reaction that is common during the treatment of syphilis, Duchenne muscular dystrophy, uveitis, and as part of a drug regimen to prevent rejection after organ transplant. It is important in the treatment of acute lymphoblastic leukemia, non-Hodgkin lymphomas, Hodgkin's lymphoma, multiple myeloma, and other hormone-sensitive tumors, in combination with other anticancer drugs. Prednisone can be used in the treatment of decompensated heart failure to increase renal responsiveness to diuretics, especially in heart failure patients with refractory diuretic resistance with large dose of loop diuretics. In terms of the mechanism of action for this purpose: prednisone, a glucocorticoid, can improve renal responsiveness to atrial natriuretic peptide by increasing the density of natriuretic peptide receptor type A in the renal inner medullary collecting duct, inducing a potent diuresis. Short-term side effects, as with all glucocorticoids, include high blood glucose levels (especially in patients with diabetes mellitus or on other medications that increase blood glucose, such as tacrolimus) and mineralocorticoid effects such as fluid retention. The mineralocorticoid effects of prednisone are minor, which is why it is not used in the management of adrenal insufficiency, unless a more potent mineralocorticoid is administered concomitantly. It can also cause depression or depressive symptoms and anxiety in some individuals. I did have cause to query certain reactions which I was experiencing, but after fine tuning, I find that taking one pill only, and not drinking alcohol has cured the minor problems I was experiencing. Thanks for that, I would just like to confirm everything that I have read about your product, it really is terrific. Whilst at the age of 60, I still have an excellent sex drive without taking MAXIDUS but what a terrific difference it has made, and I find the effect lasts more than 4 days, more like 7-10 days. I haven't told my wife yet, but oh the smile on her face, I am sure she must be wondering where I got this super dooper penis from!!! " "I have suffered from low testosterone levels for years and have not been able to achieve a firm erection in almost two years. I tried Yohimbe, Hot Plants, Stamanex, and at least 10 other brands that claimed to increase your sex drive with no results. Then, about three months ago I tried MAXIDUS, and was blown away.

    Prednisolone 21-acetate

    Flo-Pred Prednisolone Acetate Oral Suspension Side Effects., Prednisolone 21-acetate - Substance Information - ECHA

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  3. Prednisolone is a steroid medication used to treat certain types of allergies, inflammatory. Prednisolone acetate ophthalmic suspension eye drops is an. or 1,2-dehydrohydrocortisone, as well as 11β,17α,21-trihydroxypregna-1,4-diene-3.

    • Prednisolone - Wikipedia.
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    Jun 13, 2005. Prednisolone acetate · 8B2807733D, 52-21-1, LRJOMUJRLNCICJ-JZYPGELDSA-N. Prednisolone Acetate Ophthalmic Suspension USP 1%. Prednisolone 21-acetate ≥97%; CAS Number 52-21-1; EC Number 200-134-1; Synonym 1,4-Pregnadiene-11β,17α,21-triol-3,20-dione 21-acetate, 11β,17α. Structure, properties, spectra, suppliers and links for Prednisolone acetate, 52-21-1.

     
  4. Toprol-XL is a beta1-selective (cardioselective) adrenoceptor blocking agent, for oral administration, available as extended release tablets. It has been formulated to provide a controlled and predictable release of metoprolol for once-daily administration. The mechanism of the antihypertensive effects of beta-blocking agents is not fully known. However, several possible mechanisms have been proposed: (1) competitive antagonism of catecholamines at peripheral (especially cardiac) adrenergic neuron sites, leading to decreased cardiac output; (2) a central effect leading to reduced sympathetic outflow to the periphery; and (3) suppression of renin activity. Metoprolol blocks the catecholamine-induced increases in heart rate, velocity and extent of myocardial contraction, and in blood pressure, metoprolol reduces the oxygen requirements of the heart at any given level of effort. Tthe precise mechanism for the beneficial effects of beta-blockers in heart failure is not known. Toprol-XL is specifically indicated for: the treatment of hypertension, either alone or in combination with other antihypertensive agents, the long-term treatment of angina pectoris and the treatment of stable, symptomatic (NYHA Class II or III) heart failure of ischemic, hypertensive, or cardiomyopathic origin. Metoprolol - [email protected] FDA Approved Drug Products Toprol-XL New FDA Drug Approval CenterWatch Metoprolol succinate - FDA - PDF Free Download
     
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