She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine (Plaquenil) 200mg bid (6.5mg/kg) for 10 years, which was stopped one year prior to presentation. Does plaquenil prevent malaria Methotrexate sulfasalazine and hydroxychloroquine Plaquenil lyme treatment Oct 21, 2010 Funduscopic findings ranged from pronounced bull’s eye maculopathy to severe macular atrophy. SD OCT findings ranged from disruption of outer retinal integrity with preservation of foveal IS/OS photoreceptors to complete structural disorganization of the outer retina. To date, several investigators have used SD-OCT in eyes with HCQ toxicity and qualitatively evaluated thinning of the outer retinal layers or attenuation of the ellipsoid zone EZ, while others have quantitatively analysed outer retinal thickness on SD-OCT topographic map.7–10 This study aims to characterise HCQ toxicity using a newly. Bull’s eye maculopathy describes a number of different conditions in which there is a ring of pale-looking damage around a darker area of the macula. The macula can often appear to have circular bands of different shades of pink and orange. Age of onset and severity of sight loss varies, and it can be inherited in many ways. Review of systems: Blurred vision, halos, dry eye, dry mouth, gastroesophageal reflux, joint pain Pupils: Reactive to light in each eye from 5 mm in the dark to 2 mm in the light. Extraocular movements: Full, both eyes (OU) Confrontation visual fields: Full OU Intra-ocular pressure The optic nerves appeared healthy with a 0.3 cup-to-disc ratio. Past Ocular History: None Medical History: Sjogren syndrome and inflammatory arthritis, supraventricular tachycardia, anxiety, depression, peptic ulcer disease Medications: prednisone, methotrexate, amitriptyline, ranitidine, estradiol, tizanidine, diltiazem, Restasis Allergies: codeine, droperidol Family History: heart disease, arthritis, cancer Social History: occasional alcohol but no tobacco or intravenous drug use. Oct bull ey macula ellipsoid plaquenil Hydroxychloroquine Plaquenil Toxicity and Recommendations., Quantitative assessment of outer retinal layers and ellipsoid. Plaquenil and rosaceaChloroquine cos-7 24hLysosome chloroquine The condition sometimes resembles a target, or bulls-eye ring, on the retina surrounding the macula. Hydroxychloroquine retinopathy is extremely rare and is most often seen in cases where the dosage is high or the patient has been taking it for several years. Bulls-eye maculopathy is uncommon, but when it does occur, it can be devastating. Plaquenil Side Effects on Your Eyes and Vision. Bull’s eye maculopathy Macular Society. Bull's Eye Maculopathy – Causes, Complications, and.. Plaquenil is a drug that is stored in high concentrations throughout the body and is very slowly eliminated from the body. It is attracted to the retinal pigmented epithelium in the back of the eye the retina. Although rare, Plaquenil can cause significant toxicity to the eye with prolonged use. Early Plaquenil Toxicity Detected without Bull’s Eye. Bull’s Eye Retinopathy Early macular toxicity can cause stippling or. Optical Coherence Tomography OCT The macula can often appear to have circular bands of different shades of pink and orange. Age of onset and severity of sight loss varies, and it can be inherited in many ways. Bull’s eye maculopathy is a rare dystrophy, also known as benign concentric annular macular dystrophy BCAMD.