This is exacerbated by the development and confirmed spread of resistance to artemisinin drugs, the principal component of the first-line malaria treatments that are currently used worldwide. PMI-supported activities include both regional and cross-cutting activities, such as surveillance for antimalarial drug resistance, antimalarial drug quality monitoring, and regional capacity building, as well as targeted malaria prevention and control activities. Cost of aralen Chloroquine pharmacodynamics Hydroxychloroquine sulfate and psoriasis Methotrexate plaquenil and alcohol Studies conducted in some parts of Africa and in the Greater Mekong subregion indicate high ef cacy. More studies are needed to con rm its current ef cacy in endemic countries. Chloroquine remains the treatment of choice for P. vivax malaria in areas where it remains effective. Greater Mekong Subregion Although considerable progress has been made in malaria control in the Greater Mekong Subregion over the past decade, malaria remains a major concern for the international community and ministries of health in the region. The Greater Mekong subregion GMS of the Asia Pacific, which includes the countries of Cambodia, China Yunnan Province, Lao People’s Democratic Republic PDR, Myanmar, Thailand, and Vietnam, is the epicentre of artemisinin resistance. Each plan reviews the current status of malaria control and prevention policies and interventions, identifies challenges and unmet needs to achieve PMI goals, and provides a description of planned PMI-funded activities. View more » The Malaria Operational Plans below are detailed 1-year implementation plans for PMI focus countries. Greater mekong subregion chloroquine resistance A Microbial Melting Pot – The Mekong Region. - MALARIA. COM, Greater Mekong Subregion - PMI Generic plaquenil side effectsChloroquine pronunciationChloroquine in lactationCan i take plaquenil while taking my advair discus Greater Mekong Subregion multicountry grant to eliminate malaria focuses on artemisinin resistance In the lead-up to World Malaria Day 2019, and with Thailand as Chair of ASEAN gearing up to observe Malaria Week from 22 to 25 April, we examine the Global Fund’s largest multicountry grant to accelerate malaria elimination. Greater Mekong Subregion multicountry grant to eliminate.. The challenge of artemisinin resistance can only be met by eliminating.. A Microbial Melting Pot – The Mekong. - MALARIA. COM. The Greater Mekong Subregion economic cooperation program identifies and implements high-priority projects in the six countries that share the Mekong river. Within SE Asia, the Greater Mekong Subregion GMS has been one of the most dangerous foci of malaria. The GMS is comprised of Cambodia, China Yunnan province, Lao PDR, Myanmar Burma, Thailand, and Vietnam, which vary in political structure, socio-economic and financial resources, public health system, and disease ecology. The emergence and spread of fit artemisinin-resistant P falciparum parasite lineages, which then acquire partner drug resistance across the Greater Mekong subregion, threatens regional malaria control and elimination goals. Elimination of falciparum malaria from this region should be accelerated while available antimalarial drugs still remain.