One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Hydroxychloroquine sulfate 200 mg dosage Chloroquine fas associated Retinal thickness measurements of each of the nine subfields corresponding to the Early Treatment of Diabetic Retinopathy Study ETDRS areas were examined. ETDRS SD-OCT thickness measurements consist of nine separate regions, which are defined by three concentric rings centered on the fovea with diameters of 1, 3, and 6 mm, respectively. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. OCT imaging This test makes a detailed, three-dimensional image of your eye. Your ophthalmologist can use this image to look for early retinal damage. Multifocal ERG This test looks at cells in the retina called rods and cones. The test measures how well these cells respond to light. It can find retinal damage from Plaquenil. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Oct en face retina mesaurements plaquenil Automated Segmentation Measurements of the Outer Nuclear., Plaquenil Side Effects Common, Severe, Long Term - Chloroquine 500 mg buy online Aug 06, 2014 By generating high-resolution, cross-sectional images of the retina in vivo, SD-OCT may detect significant structural alterations prior to development of visible HCQ retinopathy. Previously described OCT findings in HCQ toxicity include loss of the external limiting membrane, disruption of the outer ellipsoid zone. Multimodal Imaging in Plaquenil Toxicity. How Do Ophthalmologists Look for Plaquenil Damage.. The ABCs of OCT. Hydroxychloroquine HCQ; Plaquenil retinopathy ie, HCQ toxicity is a severe complication associated with HCQ intake that can cause irreversible vision loss.1–3 Early detection of retinal toxicity is crucial since vision loss is usually permanent and cellular damage may progress despite discontinuation of treatment.2 3 Although no ideal single test exists for identification of early toxicity, spectral-domain optical coherence tomography SD-OCT plays a critical role in identifying. The observation of ORTs, using “en face” OCT, also indicates the size of these lesions inside the retina. ORT can be frequently found among AMD patients 56% of exudative and 21% of atrophic forms 3, and their incidence is probably underestimated 4. Jun 13, 2019 OCT imaging This test makes a detailed, three-dimensional image of your eye. Your ophthalmologist can use this image to look for early retinal damage. Multifocal ERG This test looks at cells in the retina called rods and cones. The test measures how well these cells respond to light. It can find retinal damage from Plaquenil.