Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. Hydroxychloroquine order online Plaquenil pregnancy category Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. The Diopsys® mfERG vision test is a painless, safe, non-invasive way for your eye care provider to objectively measure the function of your retina – the light-sensitive layer at the back of your eye. When light from an image enters your eye, it is turned into electrical energy by cells in the retina. Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). Mferg plaquenil Evaluating Hydroxychloroquine Toxicity With Multifocal., Hydroxychloroquine Plaquenil Toxicity and Recommendations. Dosage for chloroquine for salePlaquenil oct flying saucerIs hydroxychloroquine safePrimaquine and chloroquine are drugs used in the treatment infections Using multifocal ERG ring ratios to detect and follow Plaquenil retinal toxicity A review Review of mfERG ring ratios in Plaquenil toxicity. Using multifocal ERG ring ratios to detect and follow.. Multifocal ERG Test Information For Patients Diopsys. New Plaquenil Guidelines -. Hydroxychloroquine Plaquenil and chloroquine cause ocular toxicity to various parts of the eye such as the cornea, ciliary body, and retina. Chloroquine can also induce cataract formation; however, no reports of hydroxychloroquine and cataract have been reported. This article focuses upon hydroxychloroquine retinopathy. Disease Determination of hydroxychloroquine toxicity Plaquenil toxicity. In general, an abnormal mfERG indicates that the foveal cones and/or bipolar cell layers are dysfunctional and the source of vision loss. Unlike the focal ERG, mfERG also indicates the precise distribution of the retinal dysfunction. One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur.