Additionally, another exception occurred while executing the custom error page for the first exception. This article focuses upon hydroxychloroquine retinopathy. Chloroquine was originally used as an anti-malarial therapeutic. Sigma chloroquine diphosphatase Nsaid and plaquenil together Plaquenil blood plasma drops Hence, it is imperative that we become familiar with recognizing the spectrum of HVF and SD-OCT findings associated with Plaquenil retinal toxicity. Of note, SD-OCT, in combination with Humphrey visual field testing, is critical for the early detection of Plaquenil retinal toxicity. Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. Hydroxychloroquine has significantly less retinal toxicity and has largely replaced chloroquine as a treatment of inflammatory disease. Unfortunately, the retinal damage from these medications is largely irreversible, so it is critical to detect early retinal toxicity in the hopes of limiting the extent of visual loss. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. Plaquenil retinal toxicity treatment Hydroxychloroquine toxicity - EyeWiki, Hydroxychloroquine Plaquenil Toxicity and Recommendations. Plaquenil and radiation therapyRheumatoid arthritis methotrexate vs hydroxychloroquinePlasmodium falciparum chloroquine resistance first seenHydroxychloroquine topicalToo much hydroxychloroquine Patients suffering from chloroquine and hydroxychloroquine retinal toxicity were referred for study. All of the studies were carried out between 19, giving a 30-year experience. This is a retrospective study of these patients. The patient population included three cases of chloroquine and 26 cases of hydroxychloroquine retinal toxicity. Retinal toxicity to antimalarial drugs chloroquine and.. Hydroxychloroquine Plaquenil Toxicity and.. Retinal Screening for Hydroxychloroquine Plaquenil Toxicity. METHODS A prospective and continuing evaluation was made of the potential retinal toxicity of hydroxychloroquine in a cohort of 360 Greek patients followed for RA and SLE, 58 of whom have received long term treatment six years. Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use. Some side effects of hydroxychloroquine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.