Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Chloroquine treats Laboratory synthesis of chloroquine Plaquenil how fast to start working. deleted_user 05/12/2011. Hi To answer someone's question I am in my late 50's Was diagnosed March 2010 and started treatment. Nov. 2009 I went to my doctor complaining about stiff and swollen hands. does Plaquenil kick in quickly or. 12. 0. Leave A Reply. The usual starting dose of Plaquenil is 200 mg twice a day or 400 mg once a day, administered orally, in people weighing 80 kg or more. The usual dosage works for most people who take Plaquenil, but it is possible to increase or decrease the dose based on individual needs. It's important to watch for possible side effects and toxicity. Hydroxychloroquine is a DMARD. The brand name is Plaquenil. What does Plaquenil do? Plaquenil relieves pain and swelling and prevents damage to joints. How long does Plaquenil take to work? Plaquenil works very slowly. In 1 to 3 months you should start to feel better. You may continue to get better for up to 1 year. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. How long does it take for plaquenil to kick in Bone Joint Muscle - Arthritis Plaquenil - How long till it., Taking Plaquenil for Rheumatoid Arthritis Hydroxychloroquine synthesis Yep, I was just like you the first time I was taking Plaquenil. "Hurry up, show me". Well, I got really upset about 5 1/2 months into it and stopped taking it. I thought, "If this isn't going help, I am not going to take it". Well, about 2 weeks into my "stop" program, I suddenly realized it was helping me. Plaquenil - How long to take effect?. Lupus Medicines Hydroxychloroquine - Brigham and Women's Hospital. Plaquenil Uses, Dosage & Side Effects -. Hydroxychloroquine how long to take effect. Hi, i beleive Dmards can take up to 3 months to kick in so may take a bit longer to kick in. I started Hydroxychloriquine 400mg and steroids when i was first diagnosed and remember thinking 'are these tablets supposed to be doing something'. I think after about 2 weeks i felt a lot better but. Hi - I just started Plaquenil 400 mg a day two week ago and I started feeling less achy and tired a few days ago. Is it possible for it to work quicker in some people? I've heard it can take months, but I must say that I haven't felt like this since I was a kid - not achy or stiff. Has anyone had a similar I came across this page having the same question. How long does it take for Plaquenil to leave your system after discontinuing use. However, I do not want to stop taking it because of terrible side effects listed by other users of the med. I love this drug. I have never felt as good as I do now.