Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Plaquenil toxicity aao guidelines Taking methotrexate and plaquenil Statistics plaquenil maculopathy Plaquenil was originally approved by the Food and Drug Administration FDA in 1955. Plaquenil Warnings Before taking Plaquenil, tell your doctor if you have or have ever had Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. The HCQ story begins in 1638 when the wife of the Viceroy of Peru, Countess Cinchona, acquired malaria while living in the New World. Rather than getting the “approved” therapy, blood-letting, she was treated by an Incan herbalist with the bark of a tree eventually, named for the countess-Cinchona Tree. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. History of plaquenil Plaquenil Uses, Dosage & Side Effects -, Treating Lupus with Anti-Malarial Drugs Johns Hopkins. Plaquenil scarring alopecia About Plaquenil Prescription Drug Plaquenil® is a brand name for hydroxychloroquine, an antimalarial agent used for suppression and treatment of acute attacks of malaria, treatment of systemic lupus erythematosus, and rheumatoid arthritis. It may also be used for porphyria cutanea tarda, a disease characterized by blistering skin. Read more Idasek's Plaquenil history PatientsLikeMe. The Nine Lives of Hydroxychloroquine RheumNow.. Plaquenil hydroxychloroquine sulfate dose, indications.. PLAQUENIL hydroxychloroquine sulfate tablets belongs to the 4-aminoquinoline class. PLAQUENIL has been beneficial for patients with rheumatoid arthritis and lupus erythematosus, especially chronic discoid lupus. These drugs were initially used to prevent and to treat malaria but are no longer used for those purposes; more effective drugs have since been developed. Today’s AMs are hydroxychloroquine Plaquenil®, chloroquine Aralen®, and quinacrine Atabrine®. Plaquenil hydroxychloroquine is considered an older DMARD disease modifying anti-rheumatic drug. Plaquenil was actually first classified as an antimalarial drug, but it is also used to treat certain rheumatic and autoimmune conditions which are unrelated to malaria. Generally, Plaquenil is a treatment option as monotherapy used alone for mild rheumatoid arthritis or as combination.