Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Plaquenil guidelines 2016 Hydroxychloroquine sulfate hcq Hydroxychloroquine weigh A 50-year-old man presented with complaints of ring-like shadows in front of his eyes. He had been on hydroxychloroquine Plaquenil 400 mg orally twice daily for 10 years 5.14 mg/kg/day. Fundus examination revealed granular hypopigmentation in an arcuate pattern in the inferior parafoveal area bilaterally. Hydroxychloroquine Plaquenil is a chloroquine derivative used in the treatment of many diseases including malaria, rheumatoid arthritis, and systemic lupus erythematosus. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Fundus Autofluorescence FAF. Plaquenil Hydrochloroquine or Aralen Chloroquine • Annual screening after 5 years of use **Interesting, The Royal College of Ophthalmologists in Great Britain does NOT recommend routine screening for toxicity with antimalarial drug use. Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Fundus autofluorescence plaquenil Retinal Physician - CODING Q&A, Unusual Fundus Autofluorescence Appearance in a Patient. Chloroquine price canadaHydroxychloroquine plaquenil drug classHydroxychloroquine blurry vision Fundus autofluorescence images of the left eye of a 59-year-old women with sarcoidosis who received 200 mg of hydroxychloroquine sulfate twice daily for 15 years. Her visual acuity was 20/20 bilaterally with normal red light central 80-point visual fields. A fundus examination demonstrated subtle macular pigmentary change A. Fundus Autofluorescence in Hydroxychloroquine Toxicity.. Early Plaquenil Toxicity Detected without Bull’s Eye.. Multimodal Imaging in Plaquenil Toxicity. Apr 19, 2011 Specifically, spectral domain OCT is one of three objective tests now recommended for routine screening of patients on Plaquenil. The other two are multifocal electroretinogram mfERG and fundus autofluorescence FAF. Why the change in the recommendations? Fundus autofluorescence FAF is a non-invasive, high definition scan of the deeper retinal layers at the back of the eye. FAF highlights areas of metabolic stress in detail that is above and beyond that of conventional retinal cameras. Autofluorescence Fundus autofluorescence is a non-invasive diagnostic test that involves taking photographs of the back of the eye without a contrast dye. These images can help with the early detection of diseased retina in serious eye conditions such as macular degeneration, hereditary retinal degenerations, and retinal toxicity from the long term use of medications such as plaquenil.