The recurrent, painful tightening usually occurs in the calf muscles and can cause severe insomnia. The exact mechanism is unknown, but the cramps are probably caused by muscle fatigue and nerve dysfunction rather than electrolyte or other abnormalities. Plaquenil for lupus nephritis What companies make hydroxychloroquine Plaquenil and remicade Plaquenil lucite polymorphe Warning. Oral route Capsule Quinine sulfate use for the treatment or prevention of nocturnal leg cramps may result in serious and life-threatening hematologic reactions, including thrombocytopenia and hemolytic uremic syndrome/thrombotic thrombocytopenic purpura HUS/TTP. Chronic renal impairment associated with the development of TTP has been reported. I started taking Plaquenil 4 weeks ago for non specific autoimmune disease as indicated by ANA. Symptoms were low grade temperature off and on for a year, joint pain and fatigue. I have already felt some relief. Some nauseau at first but less problem with fever and joint pain. But, now I have started having stomach cramps and diarrhea. Plaquenil “ Side Effects Dizzy, upset stomach, back pain and side pain, abdominal cramps, leg cramps, rapid heart rate, anxiety and body felt covered in bruises Before taking Plaquenil my only symptom. Medications that are strongly associated with leg cramps include intravenous iron sucrose, conjugated estrogens, raloxifene, naproxen, and teriparatide. Nocturnal leg cramps are associated with vascular disease, lumbar canal stenosis, cirrhosis, hemodialysis, pregnancy, and other medical conditions. Does plaquenil cause leg cramps Plaquenil Oral Uses, Side Effects, Interactions, Pictures., Stomach problems with Plaquenil • Johns Hopkins Arthritis. Plaquenil dose for alopeciaNon aqueous titration of chloroquineHydroxychloroquine 200 mg tab side effects In rare cases, Plaquenil can cause cardiomyopathy, a chronic disease of the heart muscle. If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Hydroxychloroquine Sulfate Muscle Spasms Reports - DrugInformer. Leg Cramps A Sign of Underlying Illness?. Hydroxychloroquine - oral, Plaquenil. arm/leg/back pain, fast heartbeat, hair loss/color change, mental/mood changes. psoriasismedication may infrequently cause serious sometimes permanent eye problems or muscle damage, especially if you take it for a long time. Side effects of Plaquenil that are different from Azulfidine include stomach pain or cramps, weight loss, mood changes, nervousness, irritability, or hair loss. Side effects of Azulfidine that are different from Plaquenil include stomach upset, unusual tiredness, white patches or sores inside your mouth or on your lips, or sleep problems. It is an unfortunate reality that many important medicines can cause annoying or painful side effects. The medications with a high risk of causing leg cramps are certain asthma medications and diuretics, but countless others can have muscle twitches and spasms as even a low-risk side effect.