Additionally, another exception occurred while executing the custom error page for the first exception. Chloroquine retinopathy, is a form of toxic retinopathy (damage of the retina) caused by the drugs chloroquine or hydroxychloroquine, which are sometimes used in the treatment of autoimmune disorders such as rheumatoid arthritis and systemic lupus erythematosus. Plaquenil and lymphadenopathy Plaquenil to treat fibromyalgia Drugs administered with chloroquine If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. In this issue of Retina Today, Todd Klesert, MD, PhD, discusses practical approaches to monitoring retinal toxicity due to hydroxychloroquine therapy. We extend an invitation to readers to submit pearls for publication in Retina Today. Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. The risk of toxicity is low for individuals without complicating conditions during the first 5 years of treatment using less than 6.5 mg/kg/day of hydroxychloroquine or 3 mg/kg/day of chloroquine, and/or cumulative doses of less than 1000 gram and 460 gram (total dose), respectively. This eye toxicity limits long-term use of the drugs. Hydroxychloroquine retina Hydroxychloroquine toxicity - EyeWiki, Retina Today - RETINA PEARLS Monitoring for Hydroxychloroquine Retinal. What testing are required for plaquenil Hydroxychloroquine retinopathy It is known that some people who take hydroxychloroquine for more than five years and/or in high doses are at increased risk of damage to their retina, the light sensitive layer of cells at the back of the eye. This is known as retinal toxicity or retinopathy. Hydroxychloroquine screening. Hydroxychloroquine Plaquenil Toxicity and Recommendations.. Hydroxychloroquine Uses, Dosage & Side Effects -. Hydroxychloroquine HCQ retinopathy can result in permanent vision loss. In early stages of HCQ retinopathy, patients are usually asymptomatic with preservation of visual acuity. We aspire that our review, in conjunction with the American Academy of. Hydroxychloroquine has a lower risk of ocular toxicity, both corneal and retinal, compared with chloroquine. Smoking possibly reduces the efficacy of hydroxychloroquine, although studies have not usually confirmed this clinical impression. Hydroxychloroquine is considered safer than chloroquine during pregnancy and lactation. After six weeks on Hydroxychloroquine he got hundreds of black floaters in his eye, with intermittent flashes of light. We went to Addenbrooke's Hospital Casualty where the Casualty Doctor felt he'd had a retinal bleed due to the drug and were referred to the Eye Clinic as an emergency.