Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Hydroxychloroquine porphyria cutanea tarda moa Chloroquine lysotracker Common side effects may include headache, dizziness, ringing in your ears; nausea, vomiting, stomach pain; loss of appetite, weight loss; mood changes, feeling nervous or irritable; skin rash or itching; or. hair loss. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Plaquenil or hydroxychloroquine has been known to cause a darkened discoloration of skin and/or mucous membranes. This is considered an adverse reaction and should be discussed with your prescriber. It is important to evaluate this color change to make sure there is nothing else wrong. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Plaquenil skin changes Plaquinel changes hair color?" Lupus Community - Support Group, Hydroxychloroquine Plaquenil 2 pills per day hydroxychloroquinTeva hydroxychloroquineHydroxychloroquine and skin discoloration K2, I know that plaquenil can change both eye and skin color. I have more frequent eye exams than most lupus patients on plaquenil due to inherited cataracts and glaucoma, When my eyes are examined by my opthamologist for ANY changes, he also looks for change in eye color. Plaquinel changes hair color?" Lupus Community - Support.. Skin Discoloration and Plaquenil - Arthritis Information. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Side effects of Plaquenil that are different from Aralen include loss of appetite, weight loss, dizziness, spinning sensation, ringing in your ears, mood changes, nervousness, irritability, skin rash, or itching. Side effects of Aralen that are different from Plaquenil include blurred vision, changes in hair color, or muscle weakness. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Vision changes/loss of vision There is a chance that retinal damage will occur while taking hydroxychloroquine Plaquenil or chloroquine Aralen. This is called known as hydroxychloroquine retinopathy.