Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Plaquenil live vaccines Plaquenil otc Aug 18, 2011 Plaquenil or hydroxychloroquine has been known to cause a darkened discoloration of skin and/or mucous membranes. This is considered an adverse reaction and should be discussed with your prescriber. It is important to evaluate this color change to make sure there is nothing else wrong. Hydroxychloroquine is particularly effective for systemic lupus erythematosus SLE and discoid lupus erythematosus DLE. By reducing inflammation, hydroxychloroquine can decrease pain, swelling and stiffness of joints, and improve or clear some rashes. Which skin conditions are treated with hydroxychloroquine? These include Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Hydroxychloroquine skin Hydroxychloroquine and skin darkening Hi All. - LUPUS UK, Hydroxychloroquine Skin Support Eosinophilotaxis hydroxychloroquineAntiinflammatory plaquenilPlaquenil maculopathy mechanismsLysosomes ph and the antimalarial action of chloroquineTestimonials of people losing their hair from plaquenil MAIN OUTCOMES AND MEASURES The primary outcome was the clinical features of HCQ-induced pigmentation. Skin biopsies were performed on 5 patients, both in healthy skin and in the pigmented lesions. The statistical associations of HCQ-induced pigmentation with several variables were calculated using univariate and multivariate analyses. Hydroxychloroquine-induced pigmentation in patients with.. Hydroxychloroquine - Side Effects, Dosage, Interactions.. Hydroxychloroquine-induced Hyperpigmentation of the Skin.. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. For people with skin problems This drug may. Red skin lesions, often with a purple center severe mood or mental changes sore throat sores, ulcers, or white spots on the lips or in the mouth sticking out of the tongue stomach pain swelling of the feet or lower legs swollen or painful glands trouble with breathing, speaking, or swallowing Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth.