Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. Eye screening tests for plaquenil guidelines How long does it take for plaquenil to start working Fluoroquinolone use and chloroquine resistance development Plaquenil Hydroxychloroquine belongs to a group of medications known as anti-inflammatories and antimalarials. It is used alone or in combination with other anti-arthritic medications to treat rheumatoid arthritis. It helps to reduce pain, stiffness, and swelling in joints. Preventing eye side effects from Plaquenil American Academy of Ophthalmology Recommended dosing for women ≥ 5’7” = 400 mg a day 5 ½” – 5’6 ½ “ = 300 mg a day Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). Plaquenil eye irregularity How to Succeed in Plaquenil Screenings, Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus Hydroxychloroquine psoriasis Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so the medication can be stopped if toxicity occurs. Protecting your eyesight when taking Plaquenil Lupus.. Hydroxychloroquine Plaquenil. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes. Feb 19, 2020 Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Established maculopathy - moderate reduction VA 6/18-6/24, Bull’s eye lesion in the macula Severe maculopathy - marked reduction VA 6/36-6/60, widespread RPE atrophy surrounding the fovea End stages - severe reduction VA marked RPE atrophy with unmasking of choroidal vessels peripheral pigment irregularity with bone spicule formation, vascular attenuation & optic disc pallor.