While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. Reviews may be moderated or edited before publication to correct grammar and spelling or to remove inappropriate language and content. Does chloroquine kill cyanobacteria Retinal toxicity from chloroquine apre-19 cells Treatment/Plaquenil. Support Forums Sjogren's Syndrome. 2-3 times a week for 2 months or so. The doctor said once my body adjusted the side effect would go away. But I have been so impressed with this med that even if my body had not adjusted I would continue to use it. My legs and hips stopped aching. Hi everyone, I am wondering if anyone has had a problem with fatigue while on Plaquenil. I have been on it for about. 3 months now. At first, I was nauseous for a week or so, which the dr. told me could be a side effect. After the nausea went away it seemed like my pain got worse for a week or so, and then it gradually got better. Plaquenil hydroxychloroquine is considered an older DMARD disease modifying anti-rheumatic drug. Plaquenil was actually first classified as an antimalarial drug, but it is also used to treat certain rheumatic and autoimmune conditions which are unrelated to malaria. Generally, Plaquenil is a treatment option as monotherapy used alone for mild rheumatoid arthritis or as combination. As reviews and ratings are subjective and self-reported, this information should not be used as the basis for any statistical analysis or scientific studies."At first it made me very sick nauseous all day but figured out for me I could take it with peanut butter it coated my stomach enough to make me not nauseous. Reviews that appear to be created by parties with a vested interest in the medication will not be published. Plaquenil 3 times a week Plaquenil Dosage Guide -, Is extreme fatigue a side effect of Plaquenil? Plaquenil p450 enzymesPlaquenil retionpathySymptoms of allergic reaction to plaquenil Three months is a short time to be on Plaquenil, which typically takes at least 6 to have full effect. I've been on it for 6 now and feel much better than I did at 3 or even 4 or 5 months. I used Tylenol in the interim and it helped. However, we are all different and you may need something more. What step comes after plaquenil?. Taking Plaquenil for Rheumatoid Arthritis. What is Plaquenil? - GoodRx. Plaquenil Dosage The recommended Plaquenil dosage for malaria prevention is 400 mg once weekly, starting two weeks before the anticipated exposure. The usual starting dosage for treating lupus is 400 mg once or twice a day, and the recommended starting dose for the treatment of rheumatoid arthritis is 400 to 600 mg daily. It may be given 3-4 times per week for several weeks after the intake of Plaquenil. Acidification of the urine may also improve the urinary excretion of the drug 1, 2, 3. Prevention. The best way to prevent the occurrence of Plaquenil toxicity is to monitor the patient annually on the duration of the therapy. None of the medications, even prednisone, seemed to affect my weight. I've always been in the normal for my height range. But menopause changed all that. Over the course of two years I've gained 20 lbs and have stabilized at that weight for a couple of years now. I didn't change my eating or exercise routine zumba at least three times a week.