Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Plaquenil medication Chloroquin malaria Hydroxychloroquine poisoning Chloroquine is often part of a multi-drug regimen with other anti-parasitic medications. A cumulative dose of over 460 g or a daily dose of 2.3 mg/kg body weight/day is high risk. The latest studies show that using the patient's real weight instead of ideal weight correlates better with safe dosing. Chloroquine is rarely an option for rheumatic. Let's dive in. Melton & Thomas describe the typical safe Plaquenil dosage this way The usual dosage is two 200mg tablets per day. This is generally a "safe" dose for patients having a lean body weight of at least 135 lbs. The generally-regarded safe dosage is 6.5mg/kg/qd, thus the 135 lb. safety threshold. Nov 09, 2018 Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America. Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Hydroxychloroquine real weight safe dose New Guidelines on Hydroxychloroquine Dosage - Where Are We., Daily Plaquenil Dosage - Crunching Numbers — Plaquenil icd 10Buy plaquenil ukWhat to do if taking plaquenil makes you nauseous Dec 30, 2015 The Hopkins team seems to have found a workable middle ground – weight-based dosing up to a maximum of 400 mg/day, which is considered safe in a lean person of about 136 pounds. Three months after being prescribed hydroxychloroquine, however, just 56% of the patients were at a therapeutic level of 500 ng/mL or more. ACR Actual-weight hydroxychloroquine dosing works in SLE, up.. Hydroxychloroquine - Side Effects, Dosage, Interactions.. Ideal Body Weight for Calculating Hydroxychloroquine Dosage. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Mar 08, 2017 The ACR’s 2016 statement also does not fully endorse the AAO’s 2016 firm statement that “all patients using HCQ keep daily dosage less than 5.0 mg/kg real weight,” aside from “rare instances” when a higher dosage is needed to treat a “life-threatening disease.” He pointed out that these findings have been validated in several studies using other patient populations. He concluded that the risk is very real of developing retinal toxicity with prolonged use of hydroxychloroquine. The dose, duration, presence of renal disease and use of other drugs such as tamoxifen all contribute to the increased risk.