Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9. Hydroxychloroquine Sulfate is a potent inhibitor of autophagy. Aralen malaria prophylaxis Hydroxychloroquine cause urinary infections Please note that the molecular weight for this compound is batch-specific due to variable water content. Packaging Packaged under inert gas Warning Toxicity Harmful C Reconstitution Following reconstitution, aliquot and freeze -20°C. Stock solutions are stable for up to 3 months at -20°C. Sep 01, 2019 The molecular weight of hydroxychloroquine sulfate is 433.95, and molecular formula is C 18 H 26 ClN 3 O. H 2 SO 4. Each hydroxychloroquine sulfate tablet intended for oral administration contains 200 mg of hydroxychloroquine sulfate equivalent to 155 mg base. Hydroxychloroquine sulfate is a colorless crystalline solid, soluble in water to at least 20 percent; chemically the drug is 2-4-7-Chloro-4-quinolylaminopentylethylamino ethanol sulfate 11. PLAQUENIL hydroxychloroquine sulfate tablets contain 200 mg hydroxychloroquine sulfate, equivalent to 155 mg base, and are for oral administration. HCQ treatment inhibits RCC (renal cell cancer) cell growth, promotes apoptosis, inhibits mitochondrial oxygen consumption, and increases rates of glycolysis In vitro kinase assays: with purified proteins, recombinant S6 protein and recombinant active P70S6K are incubated in 1x kinase buffer with various amount of HCQ or RAD001 in the presence (25 μM) or absence of ATP for 30 minutes at 30°C. It prevents lysosomal acidification, thereby interfering with a key step in the autophagic process. Hydroxychloroquine sulfate molecular weight SAFETY DATA SHEET - Fisher Scientific, Hydroxychloroquine Tablets - FDA prescribing information. Ldn and plaquenilPlaquenil perioperativeCan plaquenil cause vasculitisHydroxychloroquine and prednisone Revision 11/11/2018 Page 2 of 5 Hydroxychloroquine sulfate SAFETY DATA SHEET Supersedes Revision 07/14/2015 2.3 Causes serious eye irritation. Harmful if swallowed. Material may be irritating to the mucous membranes and upper respiratory tract. SAFETY DATA SHEET Page 1 of 5 Hydroxychloroquine sulfate.. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Hydroxychloroquine Sulfate Autophagy inhibitor Read.. Hydroxychloroquine Sulfate is a synthetic derivative of quinolyl with chemotherapeutic and antibiotic properties, Hydroxychloroquine Sulfate acts against erythrocytic malarial parasites Plasmodium vivax, ovale, and malariae by concentrating in food vacuoles. It inhibits plasmodial heme polymerase and acts through other unknown mechanisms. Name Hydroxychloroquine sulfate Drug Entry Hydroxychloroquine. Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer. 2 Hydroxychloroquine is an aminoquinoline like chloroquine. 8 It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and systemic lupus erythematosus. 8. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage.