I did stop it for 2 weeks early in the treatment due to having to take a coupld other drugs that seemed to give me side effects. I just quit the plaquenil to give my liver a rest at that time. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. Hydroxychloroquine risk What is the generic name for plaquenil Plaquenil-induced toxicity usually will not occur before five years of taking the drug. “Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so the medication can be stopped if toxicity occurs. Feb. 5, 2008 -- Heart attack survivors and other heart patients may be more likely to die or suffer a heart attack in the first three months after stopping the drug Plavix, new research shows. I’ve been on plaquenil for over 20 years and just stopped taking it. I don’t think it has ever helped. I have tested negative on my ANA tests for the last 3 Year’s. Weird because I still have all the pain, plus terrible neuropathy due to autoimmune issues. Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. Can plaquenil ever be stopped abruptly My doctor has discontinued my plaquenil." Lupus Community., Study Stopping Plavix May Be Risky - WebMD Is there a natural drug substitute for plaquenil Plaquenil’s long half-life in the body can cause irreversible and progressive damage, Dr. Fung said. Similarly, one study reported that 16 women who’d taken hydroxychloroquine or chloroquine, or a combination of the agents, showed no improvement seven years after stopping drug therapy, and progression occurred in six of the cases. 2 Rx Side Effects New Plaquenil Guidelines and More - American.. Does anyone know if you have to be weaned off Plaquenil? I've.. Plaquenil Withdrawal – Life As An Anomaly. Though Plaquenil is generally regarded as safe during pregnancy, it is recommended that effective birth control is used throughout the course of Plaquenil treatment and for up to six months after treatment is stopped. I was prescribed plaquenil for Sjogrens about 5 years ago by my rheumatogist. I too was afraid of the side effects and didn't realize that the disease would worsen, so I just didn't take the plaquenil. Two years later I began having pericarditis attacks and wound up in the hospital. Had to stop taking Plaquenil. I recently decided to stop taking Plaquenil because I was having constant chest pains even more so than I usually have due to Lupus. Since I have not taken it my chest feels so much better which is odd because chest pain is not listed as a side effect.