I did stop it for 2 weeks early in the treatment due to having to take a coupld other drugs that seemed to give me side effects. I just quit the plaquenil to give my liver a rest at that time. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. Does hydroxychloroquine cause vision loss Hydroxychloroquine teratogenic effects Swelling after stopping plaquenil Chloroquine phosphate for aquarium Withdrawal syndrome is found among people who take Plaquenil, especially for people who are female, 50-59 old also take medication Lyrica, and have Fibromyalgia. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly. So that's the update. The lesson here is - for those who need to go off plaquenil, be careful about just going off it cold turkey. Obviously some of CAN do that, but if you don't know if you're one of them - better to be on the safe side and wean slowly. Take it from me! I am feeling much better after bumping my dose back up over the last few. It's ok to stop plaquenil without weaning, but I do recommend that if you feel you can wait til Monday, wait, and talk with your rheumy then. I felt that plaquenil wasn't helping, and was causing digestive problems for me, so with my dr. ok, I went off it. Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. Do you have to wean off hydroxychloroquine Can I stop my immunosuppressant abruptly or do I need to wean., Let me tell you what weaning down from Plaquenil is like. Chloroquine phosphate usesPlaquenil causes leg weakness in psoriatic arthritisWhat happens if i stop taking plaquenilPlaquenil cause low wbcDoes plaquenil cause heart palpitations People feel different symptoms of low blood sugar. It is important that you learn which symptoms you usually have so you can treat it quickly. Talk to your doctor about the best way to treat low blood sugar. Hydroxychloroquine can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. If. Hydroxychloroquine Oral Route Precautions - Mayo Clinic. Can you quit plaquenil cold turkey, or have to wean. Stopping Plaquenil - General Discussion - Life With Lupus. If you really need to get off it, I would taper down slowly, very slowly. There is a similar posting on Healthunlocked, "Why oh why did u stop taking plaquenil." You may want to check it out. I do go for intense eye examinations every 6 months to see if there is a difference in my eyesight from my base examine. I do have SJS also. Welcome to Sclero Forums! It is delightful to have you join us. I think your experience with going off plaquenil is very helpful for the rest of us to know about. You can let go of being angry at yourself, if you want. You didn't know for sure, ahead of time, that your health would worsen when you went off of plaquenil, did you? Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. If you're gonna experiment, I went off it cold turkey as it didn't hurt to do it that way, but you better get back on before the summer or you could experience a flare-up.