Tamoxifen pregnancy success

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  1. JONER Moderator

    Tamoxifen pregnancy success


    What this means is that more and more women are facing questions involving pregnancy and fertility after being diagnosed. Although this shift is causing researchers to pay more attention to these issues, it is no simple task to study pregnancy in women with breast cancer, or in women who have been treated for breast cancer. The difficulty is finding women with the same cancer status and fertility outcomes, who can be compared in randomized clinical trials. Until recently, most doctors have worried pregnancy might spark hormonal changes in breast cancer survivors that could spur the disease’s return, often counseling women against getting pregnant after they recover. Although nearly all of the studies to date have focused on small groups of women, this limited research is beginning to answer some of the most crucial questions about the safety of pregnancy for women with a personal history of breast cancer and the safety of breast cancer treatment during pregnancy. At the European Breast Cancer Conference held in March of 2010, the Royal College of Obstetricians and Gynecologists reported that pregnancy is safe for breast cancer survivors. They further advised that women should wait as long as five years after treatment before becoming pregnant. Tamox-in-Toronto wrote: Been on tamoxifen for 1.5 years. I went into temporary menopause for 10 months after chemo. As I am now 38, and my ovarian reserve took a massive hit from chemo, and I need to have a full hysto because I am BRCA positive, I feel tremendous pressure to try to have a baby now. I was diagnosed six weeks before our wedding at age 35, just as we were trying to conceive. My period is very light, but its a period nonetheless. My oncologist gives me dodgy answers about whether it is safe to go off tamoxifen early. It seems one needs to be on tamoxifen for 2 or 3 years to realize a benefit. So, I am considering going off tamoxifen in January 2014 and ttc. But I will also admit, I am afraid of going off tamoxifen early and worried about the effect pregnancy could have on recurrence. My ovarian reserve is super low now (.6), but my FSH is good at 8. Log in to post a reply Feb 22, 2013 AM Moderators wrote: Hi Tamox-in-Toronto, and welcome to BCO.

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    However, there is insufficient data for the possible consequences of tamoxifen exposure during pregnancy. Here, we are reporting a case with inadvertent usage. Jun 11, 2015. Pregnancy After Breast Cancer Steph's Story. What if I take a break, get pregnant, go back on Tamoxifen and we all live happily ever after? So, I am considering going off tamoxifen in January 2014 and ttc. of going off tamoxifen early and worried about the effect pregnancy could have on. I never had children and tried fertility before treatment with no success.

    I always took it for granted that I would, someday, have children. I never grappled with the decision of whether or not motherhood was for me, or thought of what my life might be like without kids. A week before my doctor’s appointment, I found a lump in my breast. I made mental notes of my favourite baby names, and imagined what they might look like. I changed the purpose of the appointment to talk about boobs instead of babies. After meeting and marrying my husband, the desire to start a family grew stronger. And after several tests and a couple weeks of waiting, I received the diagnosis. I had just celebrated my 28birthday and had been married for less than a year. To say things were not going according to plan would be a massive understatement. I dreamed and planned and let my mind wander to a future that I thought was secure. And, ironically, I did end up coming off my pill, but not for the reason I had intended; rather, the breast cancer I had was fueled by estrogen (a main ingredient of the birth control pill), so I was told to immediately stop taking it. In the same conversation where I learned I had an invasive, aggressive breast cancer, I also learned that the chemotherapy I’d need to undergo could cause fertility issues. At first anything other than the fact that I might die seemed inconsequential. I made an appointment with my doctor, thinking maybe we’d broach the subject of stopping my birth control pill. But after taking some time to process everything and meeting with a fertility specialist, the reality set in that there was now a possibility I’d never have children. I considered undergoing fertility preservation treatment and went through the initial steps, but ultimately pulled out at the eleventh hour due to timing factors, enrolling myself in a clinical trial, and not being comfortable at that point with injecting hormones into my body. Unfortunately, hormonal therapy for cancer comes with a whack of side effects. Cancer has a way of forcing you to be decisive.) The way I usually make my decisions is to do read up on all the research and literature I can possibly find. Susan Love writes, “We are frequently asked what would happen if a woman stopped taking tamoxifen between two years and five years, and the truth is that we just don’t know because we have no studies that have looked at that question. We decided to accept the risks, and hope for the best. Because my cancer was hormone-sensitive, I need to take a drug called Tamoxifen that is proven to reduce the risk of the cancer returning and possibly spreading to another part of my body. The biggest one for me is that I’ve been told not to get pregnant while taking it, due to its potential to cause birth defects. …Because there is no data to support stopping early, this has to be a personal decision, and it is undoubtedly not an easy decision for many women to make.” I constantly toss scenarios around in my head, playing out the various possibilities. If you're having problems getting pregnant because of irregular menstrual cycles or a lack of ovulation, your doctor may recommend you to use the fertility drug tamoxifen. Tamoxifen, also referred to as Nolvadex, is used to treat female infertility by triggering ovulation. When ovulation occurs on a regular basis the odds of conception increases and pregnancy becomes more likely. Read on to find more about this infertility treatment and whether Nolvadex is right for you. Nolvadex works to block estrogen, so it's known as an estrogen antagonist. Although, estrogen is beneficial in small amounts, it can produce infertility problems when an excessive supply of estrogen is produced. Nolvadex is also used to preserve fertility in women with breast cancer as they undergo cancer treatment.

    Tamoxifen pregnancy success

    Comparison between tamoxifen and clomiphene citrate. - eJManager, Pregnancy After Breast Cancer Steph's Story Rethink Breast Cancer

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  6. Aug 20, 2017. A breast cancer drug improves IVF success rates in women over 40, claims. She says Tamoxifen improves egg quality & chances of pregnancy.

    • Breast cancer drug improves IVF success rates, claims Clinic..
    • Breast Cancer Topic Coming off Tamoxifen early to become pregnant?.
    • Tamoxifen in Pregnancy Safety Concerns - Verywell Health.

    Jan 7, 2003. Also, many experts do not recommend that breast cancer patients get pregnant for at least two to five. Tamoxifen then became a drug used to treat infertility. The women in Oktay's study may have had success because the. Jan 13, 2016. Women are advised not to become pregnant while taking tamoxifen because it can harm a fetus. Tamoxifen is not believed to directly affect. Tamoxifen. Tamoxifen Nolvadex has been used for over 40 years to treat hormone-receptor positive early, locally advanced and metastatic breast cancers.

     
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