Listing a study does not mean it has been evaluated by the U. Hydroxychloroquine and is an established, effective, safe and inexpensive therapy, widely used in other autoimmune diseases such as lupus and rheumatoid arthritis. The study is open to adults diagnosed with certain types of vasculitis, called Granulomatosis Polyangiitis (GPA), Microscopic Polyangiitis (MPA) or Eosinophilic Granulomatosis with Polyangiitis (EGPA). Plaquenil hand oa Plaquenil uses Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. The purpose of this study is to find out whether hydroxychloroquine, in addition to background treatments, reduces disease activity in patients with Anti-Neutrophilic Cytoplasmic Autoantibodies ANCA Vasculitis, a group of autoimmune diseases. Hydroxychloroquine and is an established, effective. Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. Participants will be randomly placed in 1 of 2 groups. One group will receive hydroxychloroquine and the other will receive placebo. 76 ANCA Vasculitis participants will be recruited (38 in each treatment arm) from UK vasculitis specialist centres over 2 years. Participants will be eligible if they are treated with background medication to control their vasculitis disease and have a low level of disease activity as defined by a Birmingham Vasculitis Activity Score (BVAS) of greater than 3. Plaquenil treatment for vasculitis Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus., Hydroxychloroquine in ANCA Vasculitis Evaluation - Full. Chloroquine buy on line Treatment of urticarial vasculitis is based on systemic effects of the disease, extent of cutaneous involvement, and previous response to treatment. For patients with cutaneous involvement only, antihistamines or nonsteroidal anti-inflammatory drugs NSAIDs may provide symptomatic relief. Urticarial Vasculitis Medication Antihistamines, Anti.. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. New Use for an Old Drug Hydroxychloroquine for the Treatment.. Plaquenil hydroxychloroquine "I felt better than I have in 20 years! After 20 years on NSAIDS needed for Lyme arthritis, my kidneys were affected, and when I stopped NSAIDS cold turkey, it was amazing how much pain my body was in. Now a year into Plaquenil I feel like a new person. Get eyes checked every 6 months. Plaquenil and Vasculitis - from FDA reports Summary Vasculitis is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years, also take medication Prednisone, and have Osteoporosis. Background There is an unmet need for a less toxic, corticosteroid sparing therapy in ANCA vasculitis AAV, as up to 50% of patients relapse by 5 years and 20% have sub-optimal disease control. Hydroxychloroquine HCQ has been effective and safe in autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis.