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    Just a year after launching their generic version of Pfizer’s erectile dysfunction (ED) drug Viagra (sildenafil), Teva is taking on another blockbuster as they prepare to debut generic Cialis (tadalafil) in the US. Teva has secured fist-to-file status for generic Cialis which will grant them 180 days of market exclusivity before other generic pharmaceutical companies have a chance to get their own versions approved. “We’re proud to offer an affordable treatment option for the estimated 30 million men affected by ED, many of whom will also have symptomatic [benign prostatic hyperplasia] which is estimated to affect 15 million men in the United States,” said Hafrun Fridriksdottir, Teva’s Executive Vice President and Head of Global R&D. The company will be marketing four dosages (2.5 mg, 5 mg, 10 mg, 20 mg) in the country which will give patients the opportunity to access a generic substitution for their Cialis prescription. According to data from IQVIA, Cialis brought in close to 1.93 billion in US sales as of July of this year, offering Teva an opportunity to cash in on this lucrative market. According to an article published in Fierce Pharma, sales of Eli Lilly’s Cialis took a hit in 2017 when generic Viagra – including Teva’s version – began hitting pharmacy shelves. Teva’s generic Cialis will almost certainly further erode sales, with some analysts saying annual sales could drop as low as $55 million in the next four years. Teva Pharmaceutical Industries has announced the US launch of their generic sildenafil citrate (Viagra) tablets, according to a company press release. Sildenafil tablets are a phosphodiesterase-5 (PDE5) inhibitor indicated for the treatment of erectile dysfunction (ED). Additionally, officials with Teva are offering a sildenafil tablets savings card for patients who meet certain requirements, allowing them to pay as little as $0 out-of-pocket cost with a maximum benefit of up to $100 per fill, for up to 6 sildenafil tablets prescriptions. According to its safety information, sildenafil tablets should not be used in men for whom sexual activity is inadvisable due to their underlying cardiovascular status, since the medication can cause cardiac risk. Concomitant use of sildenafil tablets and alpha-blockers or anti-hypertensives may lead to hypotension. Concomitant administration of sildenafil tablets and the protease inhibitor ritonavir substantially increases serum concentrations of sildenafil. Common adverse reactions associated with sildenafil tablets include headache, flushing, dyspepsia, abnormal vision, nasal congestion, back pain, myalgia, nausea, dizziness, and rash.

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    Question #1: Can you confirm that the software will support both sensors simultaneously? It is also possible to open the software a couple of times and connect each instance to a sensor. Answer #1: You can connect several sensors to your PC via USB or Ethernet and select one of them from the present ones. Question #2: Our final test protocol requires that the device under test be cycled and measured three times, with an approximate 3 second delay between cycles, and all data recorded. Is the software capable of supporting this profile with one button push? Answer #2: Generally, yes, as far as I understand this correctly. We can use a trigger torque to start the graph recording, and we can have a delay time to bridge the delay between the measurements, so that we then get one graph without interruptions then the torque drops down below the trigger torque. Question #3: What documentation is provided for the software? Question #4: What training provision comes with it? If you’re looking for a less costly Viagra, you might want to ask your doctor about sildenafil. It's the active ingredient in both branded Viagra and the drug Revatio, which is a lower dose than Viagra and approved to treat pulmonary arterial hypertension. The important difference: Generic Revatio is available for a fraction of the cost. "Generic Revatio is considerably less expensive, and it is the same drug as Viagra with the same safety and effectiveness," says Bradley Anawalt, M. D., an endocrinologist and professor of medicine at the University of Washington in Seattle who chairs the Endocrine Society's Hormone Health Network. At a lower dose, sildenafil is approved to treat pulmonary arterial hypertension—the higher dose is reserved for treating erectile dysfunction (ED). Anawalt explains that there's a chance your insurance might not cover it to treat ED.

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