It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Chloroquine food cravings Plaquenil is it good for gout Rheumatoid arthritis is a chronic disorder for which there is no known cure. Fortunately in the last few years, a shift in strategy toward the earlier institution of disease modifying drugs and the availability of new classes of medications have greatly improved the outcomes that can be expected by most patients. It can take up to 3 months to get the full benefits of Plaquenil. However, I took one dose, and the next day, my fatigue was gone. I still ache, but I have belief it will be gone in a few months! Just hang tight. WILL get better. Aug 14, 2017 Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. According to the Mayo Clinic, it can take up to six months' constant use before an effect is seen in RA. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. How long to take plaquenil for ra The Risk of Retinal Toxicity with Plaquenil, Plaquenil For Rheumatoid Arthritis Arthritis Forum. Plaquenil and sjogren's Damage to the retina, the light sensitive portion of the inner eye, can occur with long-term use of Plaquenil or chloroquine Aralen. With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus Center. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Treatments for Rheumatoid Arthritis. Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. Hi Guys, I haven't been here for a while - just checked in and found this question on Plaquenil - for me it took approx nine weeks to begin to work - I'm only taking 200mg per day so far - it seemed to stop working a few weeks later - most days are pretty good I s'pose but I drop nearly every afternoon. And how did we make the leap from treatment of malaria to the recognition of Plaquenil’s value in the management of lupus and rheumatoid arthritis? In the treatment of SLE, Plaquenil is widely regarded as a cornerstone drug in the management of skin & arthritis symptoms.